As millions of Americans shelter in place, it’s clear that very little matters as much as a safe, stable home. This is especially true for our children. Decades of public health research show that conditions during pregnancy and early childhood are some of the most important factors influencing lifetime health—affecting physical well-being and educational and behavioral outcomes. The COVID-19 pandemic adds new importance to housing stability for children, families, and our communities. We all have roles to play in improving housing stability and reducing the risks of COVID.