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IPVS Webinar - HPV latency: more questions than answers
The ability of papillomaviruses to establish infection at human epithelial sites that is largely undetectable by most routine molecular diagnostic tests is indisputable. However, there remains considerable disagreement about what this ‘test negative, infection positive’ state represents (i.e., latency or very low viral copy persistence), how common it is at the anogenital or oral/oropharyngeal sites in women and men, and what risk of HPV-associated cancers this state of infection confers to an individual across the lifespan.

Drs. Bettie Steinberg and Patti Gravitt will take an interdisciplinary look at the evidence and lead a discussion to help the papillomavirus community reflect on what is known and unknown about HPV latency, why it may be important to accelerate research efforts to address the remaining uncertainties, and how we may frame the research questions using novel study designs and interdisciplinary perspectives.
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