Obtaining pure fractions of antibodies and proteins is crucial in many applications, including the development of medicines and vaccines, for structural and characterization studies or as raw materials used in biological assays. Antibody and protein purification is conventionally performed using column affinity chromatography, a gold standard technique that yields high recoveries and purities. It is a delicate process though, and usually involves long sample preparation times and has a relatively limited throughput.
Magnetic separation is an alternative yet powerful purification technique that has been gaining popularity in recent years. Apart from high recoveries and purities, it also simplifies the sample preparation process while simultaneously increasing throughput due to the inherently rugged nature of the method.