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Bench to Bedside: How does a Drug Treatment get made?
Join us as Drs. Jantzie and Robinson walk us through the process of drug innovation and all the challenges, successes, funding, and time that come with it. There are many steps in this process from preclinical testing through all the phases of clinical trials. They will share with us why pre-clinical drugs do not always make it to the market. They will highlight their own treatment discovery that they are testing, erythropoietin and melatonin as it is entering the clinical phase of testing.

May 9, 2023 07:00 PM in Eastern Time (US and Canada)

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Shenandoah Robinson, MD
Professor, Neurosurgery @Johns Hopkins University | Baltimore, MD
Dr. Shenandoah Robinson is a nationally recognized expert in the treatment of pediatric epilepsy, spasticity and hydrocephalus. Her research focuses on clarifying how early insults to the developing brain lead to deficits, such as cerebral palsy and epilepsy, and how to mitigate these deficits with neurorestorative agents. She has built on using these neuro-immunomodulatory cocktails to prevent various types of acquired hydrocephalus. As a prolific researcher and award-winning teacher, she has written dozens of peer-reviewed professional journal articles and more than 15 book chapters, and she has mentored numerous pediatric neurosurgery trainees. Dr. Robinson serves on the Executive Councils of the American Society of Pediatric Surgeons (ASPN) and the American Academy of Neurological Surgery. She is also a Director of the American Board of Pediatric Neurological Surgery, and previously served on the Editorial Board of the Journal of Neurosurgery: Pediatrics.
Lauren Jantzie, PhD
Associate Professor of Pediatrics, Neurology and Neurosurgery @Johns Hopkins University | Baltimore, MD
Dr. Jantzie is a neuroscientist whose independent research program serves a medically disadvantaged patient population that includes infants and children with early brain injury living in metro, rural and economically depressed communities. The Jantzie lab is dedicated to understanding the pathophysiology, diagnosis and treatment of central nervous system insults that result in cerebral palsy, hydrocephalus, pain, and neuropsychiatric disorders. The goal of Dr. Jantzie’s laboratory is to identify novel drug targets, agents, biologics and cell-based therapeutics to facilitate neurological recovery and brain repair. Through diverse, expansive and translational mechanistic studies and preclinical modeling, she is able to connect her research program to clinical practice on a daily basis.