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Topic

What’s New in GastroPlus® v9.8.3?

Description

Learn about the new and improved functionality to drive advances to PBBM/PBPK applications from discovery through post-approval.

Key enhancements include:
• Flexible handling of dose regimens to allow for administration of any Additional Dosage Routes model during simulations
• New validated swine PBPK model to drive pharmaceutical and veterinary medicine research
• New enzyme and transporter expression levels across species to expand the virtual population databases
• New validated NAFL and NASH disease populations with options to inform the NAFLDsym® software
• Improved reporting templates for the Monolix™ software to support the statistical analysis of virtual PBPK population results
In this webinar, we will demonstrate how these new features in GastroPlus support research across departments, inform regulatory interactions, and communicate with all software across the Simulations Plus universe!

Presenters:
Haiying Zhou, Sr. Director, Simulation Technologies
Neil Miller, Vice President, Simulation Sciences

Time

Jan 11, 2023 08:00 AM in Pacific Time (US and Canada)

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Message preview	Hi there, You are invited to a Zoom webinar. When: Jan 11, 2023 08:00 AM Pacific Time (US and Canada) Topic: What’s New in GastroPlus® v9.8.3? Register in advance for this webinar: https://us02web.zoom.us/webinar/register/WN_21xNQJvLQfiq7k0oT5oU4g After registering, you will receive a confirmation email containing information about joining the webinar. ---------- Webinar Speakers Neil Miller (Vice President, Simulation Sciences @Simulations Plus) Neil Miller is the Vice President for Simulation Sciences at Simulations Plus, driving the development and application of physiologically based pharmacokinetic (PBPK) modeling software tools for the pharmaceutical, biotechnology, chemicals, and consumer goods industries. Previously he was at GlaxoSmithKline for over 20 years gaining experience of working in the pharmaceutical industry. His last position was as a Scientific Director within the Systems Modeling and Translational Biology group, leading a team of advanced PBPK specialists that provided end-to-end mechanistic modelling for drug discovery and development. Key activities included predicting efficacious human doses at Candidate Selection (CS) and supporting drug product development with physiologically based biopharmaceutics modeling (PBBM). Haiying Zhou (Senior Director, Simulation Technologies @Simulations Plus) Haiying Zhou is a Senior Director of Simulation Technologies at Simulations Plus. She joined Simulations Plus in 2009 and focused on the development of modeling and simulation software for quantitative understanding of the pharmacokinetics and pharmacodynamics of drug candidates (GastroPlus). She also spent two years in the development of DDDPlus for the simulation of in vitro dissolution of active pharmaceutical ingredients and formulation excipients. She received her Ph.D in Biomedical Engineering from Case Western Reserve University (CWRU) in 2009. Her research interests in CWRU include multi-scale mathematical modeling of gas transport and cellular metabolism with emphasis on the metabolic regulation of physiological systems.

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