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Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies
Join us on July 21 at 9 am Pacific / 12pm Eastern to hear Drs. Jerry Heindel, Gail Prins, Ana Soto, Cheryl Rosenfeld, and Heather Patisaul discuss the Consortium Linking Academic and Regulatory Insights on bisphenol A Toxicity (CLARITY-BPA) program and present the new publication, “Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies.”

The CLARITY-BPA program is a comprehensive “industry-standard” Good Laboratory Practice (GLP)-compliant 2-year chronic exposure study of bisphenol A (BPA) toxicity that was supplemented by hypothesis-driven independent investigator-initiated studies, funded and coordinated by the US FDA, the National Toxicology Program, and the National Institute of Environmental Health Sciences, Division of Extramural Research and Training. The fourteen funded investigator-initiated studies were focused on integrating disease-associated, molecular, and physiological endpoints previously found by academic scientists into an industry standard guideline-compliant toxicity study. Thus, the goal of this collaboration was to provide a more comprehensive dataset upon which to base safety standards and to determine whether industry-standard tests are as sensitive and predictive as molecular and disease-associated endpoints.

This new publication integrated the findings from eight of the investigator-initiated studies into a comprehensive overview of the observed impacts of BPA across the multiple organs and systems analyzed. This is the first study to use such a whole-body integrative approach across a number of data-sets with multiple investigators and with organs from the same animal. By using this approach, researchers show that exposure to even a low dose of BPA currently considered safe by the FDA leads to simultaneous effects in multiple organ systems and at all ages examined.

https://www.healthandenvironment.org and select this webinar from the list at the bottom left of the homepage.

Jul 21, 2020 09:00 AM in Pacific Time (US and Canada)

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