(October 27, 2021) Webinar: GSK3 Inhibition and Muscle Wasting Disorders: Muscular Dystrophy and Spaceflight

Muscles are vital for everyday life, from every move we make to every beat of the heart. Conditions that lead to muscle wasting can drastically reduce our health and quality of life. This presentation will discuss the possibility of inhibiting an enzyme called glycogen synthase kinase 3 (GSK3) for the treatment/management of muscular dystrophy and spaceflight.

Without providing too much detail we will show our results with tideglusib treatment - a clinically advanced GSK3 inhibitor - on mdx mice. We will also discuss some of our ideas moving forward with spaceflight and how we plan on leveraging new infrastructure.

Objectives:

- The importance of muscle health for overall health
- Glycogen synthase kinase 3 and its role in regulating muscle size and composition
- Calcium regulation in the heart
- Muscular dystrophy
- Spaceflight

01:01:00