With vaccination programs being rolled out in many countries, is the post-COVID-19 era coming soon? Has the pandemic accelerated the development and the adoption of telemedicine, AI & digital health? What role will they play after the pandemic? In APTOS 2021, we will explore the evolution, latest advances and the regulatory & social perspectives of telemedicine, AI & digital health. Don't miss the launch of the Big Data Competition that focuses on the prediction of anti-VEGF treatment outcomes on patients with diabetic macular edema.