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Our globe is facing the alarming issues of extreme climate
change, uncontrolled risky population, scarcity of food and
water, limited energy resources and lack of sustainability in our
approaches. In this scenario, to produce synthetic drugs and
chemicals which are the essentials of our society and economy,
using greener and efficient protocols are of great interest as
heavy metals have been historically used in the synthetic
process which have limited their potential applications in the
chemical biology because of its cytotoxic and eco-adverse
effects. The current research is focused on the metal-free
synthesis of triazole embedded molecules which are highly
demanding non-natural compounds with potential bio-active
applications such as anticancer, non-nucloside reverse-
transcriptase inhibitor, anti HIV, and antituberculosis etc.
Moreover, this metal-free approach is further applied to
peptoids and antibiotics modification.

Sep 8, 2022 12:30 PM in Santiago

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