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Topic

HPV Latency is it real and does it matter?

Description

Epidemiology studies have shown intermittent detection of the same HPV type occurs in some women. In addition, women that report celibacy have been shown to have incident infections. These observations have brought into question the role of latency vs new cervical infections from either a partner or autoinoculation. Data will be presented that show the strong association with sexual behavior and repeat detection. Clinical data shows that a positive HPV cervical cancer screening test preceded by a negative test is associated with very little risk of CIN 3+ suggesting these are new infections. However, this also suggests that if this is a latent infection, clinically it may not be relevant as well. Data will be shown that intermittent positive tests over prolonged periods, however, do represent risk of CIN 3+ in the rare case.

Presentation 30 minutes, 30 minutes for Q&A. This webinar is live and free of charge.

Time

Feb 17, 2021 05:00 PM in Amsterdam

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Message preview	Hello, You are invited to a Zoom webinar. When: Feb 17, 2021 05:00 PM Amsterdam Topic: HPV Latency is it real and does it matter? Register in advance for this webinar: https://us02web.zoom.us/webinar/register/WN_Z_yLslmQSVGMlUFuEi-1uA After registering, you will receive a confirmation email containing information about joining the webinar. ---------- Webinar Speakers Margaret Stanley (Professor @University of Cambridge, UK) Margaret Stanley is Emeritus Professor of Epithelial Biology, Department of Pathology, University of Cambridge, Honorary Fellow of Christs College, Fellow of the Academy of Medical Sciences and Honorary Fellow of the UK Royal College of Obstetricians and Gynaecologists. Anna-Barbara Moscicki (Professor @University of California, Los Angeles (UCLA), USA) Dr. Moscicki is Professor of Pediatrics at UCLA, Division Chief of Adolescent and Young Adult Medicine, and Associate Executive Chair for Clinical Research. Dr. Moscicki’s career has focused on adolescent gynecology and STI research with a specific focus in Human Papillomavirus, HIV infection and mucosal immunology. Dr. Moscicki was the PI of a natural history study of HPV in adolescents and young women that followed women for 25 years, one of the longest running HPV cohorts. Her work on the natural history included defining persistence and clearance, mucosal and systemic immune responses to HPV and the role of the microbiome and HPV clearance. John Doorbar (Professor @Division of Virology, Department of Pathology, University of Cambridge, UK)

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