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A novel platform for single-cell detection of multiple CRISPR-edited gene modifications
Have you ever wondered what were the exact indels that were made to the DNA after genome editing experiments? Have you wondered what percentage of the cells had certain edits? Have you ever wondered whether the edits were made on only one chromosome or both chromosomes to reveal the zygosity of the edit? Using single-cell DNA sequencing on the Tapestri Platform, the Wu lab from Dana Farber did just that. Come join us as Dr. Elisa Ten Hacken shares novel data on how they used the Tapestri Platform to better understand their CRISPR mouse models of chronic lymphocytic leukemia (CLL).

Aug 18, 2020 09:30 AM in Pacific Time (US and Canada)

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