Clinical studies have shown that microbial post-biotics in the gut are altered in different skin disease states and can have a measurable impact on skin outcomes. In particular, the production of short-chain fatty acids in the gut and modulation of those short-chain fatty acids in circulation can alter the presence of acne and inflammation in the skin. Studies in those with non-cystic acne in skin of color will be discussed. We will also discuss the role of postbiotics such as carotenoids in the GI tract may have an impact on the resilience of the skin. Finally, we will explore how modulations to the gut microbiota can change post-biotic expression. In addition to gut derived postbiotics, we will also explore the use of topical probiotics and the clinical evidence for their role in skin disease and inflammation.
- Identify the differences between prebiotics, probiotics, and postbiotics
- Describe how gut derived post-biotics are related to skin health and skin pigmentation, especially in acne
- Evaluate the evidence for the role of topical postbiotics on skin barrier function, inflammation and dyspigmentation