When humanity confronts a threat to life as we know it, which includes widespread human suffering and death, conventional perspectives on the nature of reality, including the divine reality, are thrown into a tailspin. This is the old theodicy question that troubles many faithful religious devotees, including Christians. Confronting the Coronavirus, the question across the globe becomes especially acute. Each of the world’s religions has their own answers to the question “Why?” but answers seem never to be satisfactory. There are even multiple answers to the question provided by the writers of the Christian Bible. In this talk, I simply want to present two complementary perspectives, one called the etiological model, with three approaches, and the other a teleological model coming from a different direction. One approach seeks to answer the cause of suffering; in contrast, the other is focused on the purpose of suffering. The interesting thing for us to explore is what happens when these two distinctly different models meet at the nexus of science. At the end, you might feel that the original question still has not been answered, but the hope is, at least now, you will see that – even without an answer – we have no excuse for ignoring our responsibility. Human empathy still calls us to do all we can to ease the torment of those afflicted with suffering.