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Biomarker Discovery with the MiRXES ID3EAL Technology: Tear fluid microRNA profile as a potential biomarker to predict response to anti-VEGF treatments for Diabetic Macular Edema (a pilot study)

Description

There is currently an unmet clinical need for a diagnostic biomarker to predict response to anti-VEGF treatment in DME. In this pilot study, Asst. Prof Su and team performed a systematic comparison of the miRNA profiles generated from tears, aqueous, and serum and identified potential miRNAs in tears to differentiate between responders and suboptimal responders to anti-VEGF therapy. They reported novel miRNAs and provided insight into biological pathways implicated in DME. In addition, they identified tears as a non-invasive source of biofluid to discover novel miRNA biomarkers. Further validation studies in larger independent cohorts are needed to determine the predictive performance of these miRNA candidate biomarkers prior to establishing a panel for use in clinical practice.

In this webinar, we speak with Asst. Prof Su to find out more about her interesting study.

Time

Nov 12, 2020 02:30 PM in Singapore

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Message preview	Hi there, You are invited to a Zoom webinar. When: Nov 12, 2020 02:30 PM Singapore Topic: Biomarker Discovery with the MiRXES ID3EAL Technology: Tear fluid microRNA profile as a potential biomarker to predict response to anti-VEGF treatments for Diabetic Macular Edema (a pilot study) Register in advance for this webinar: https://us02web.zoom.us/webinar/register/WN_uz3o_6BATXiaCZv54mvDBQ After registering, you will receive a confirmation email containing information about joining the webinar. ---------- Webinar Speakers Dr. Su Xinyi (Assistant Professor @Yong Loo Lin School of Medicine, NUS) Dr Su Xinyi (PhD, MMed, FAMS, MBChir) is the Principal Investigator of the Translational Retinal Research Laboratory of IMCB, A*STAR, Consultant Ophthalmologist and Research Director of the Department of Ophthalmology, National University Hospital, and an Assistant Professor at the Yong Loo Lin School of Medicine, NUS. She is passionate about building bridges between science and medicine. Her research interests are in translational research for retinal surgery and therapeutics. Xinyi has published several book chapters and numerous journal articles in, inter alia, Nature Biomedical Engineering, Nature Structural Molecular Biology, and Lancet Global Health. She has been awarded more than SGD10 million of competitive research funding. She is the recipient of multiple global and national awards, including, most recently in 2019, the Young Ophthalmologist Award from the Asia-Pacific Academy of Ophthalmology.

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